Journal: Antibiotics
Article Title: Development of a UHPLC-UV/Vis Method for Simultaneously Determining Six Beta-Lactam Antibiotics in Plasma: A Tool for the Clinical Implementation of Therapeutic Monitoring of Beta-Lactams
doi: 10.3390/antibiotics14060613
Figure Lengend Snippet: Internal validation. Correlation between two analytical methods: HPLC commercial kit by Chromsystems and our own analytical method developed. The blue area represents the 95% confidence bounds.
Article Snippet: In order to test the validity of the developed method, samples of real patients from different clinical areas of the University Hospital of Santiago de Compostela were analyzed and the concentration was measured in parallel with this method and with the antibiotic HPLC kit 61,000 marketed by Chromsystems Instruments & Chemicals GmbH (Gräfelfing, Alemania) and certified according to the ISO 13485 standard [ ].
Techniques: Biomarker Discovery